Mixing Instructions

  • The veterinary surgeon is responsible for determining antibiotic type and dosage to be used. Antibiotic is not included in kit.
  • Four mixing techniques are provided for optimal mixing of powdered and liquid antibiotics:
  1. Standard – Powder
  2. Standard – Liquid
  3. Non-Standard – Powder
  4. Non-Standard – Liquid
  • To ensure proper mixing, prepare required materials and calculate dosage prior to beginning.
  • A Set Time Chart is provided to specify recommended mixing
    technique for commonly used antibiotics.

Set Time Chart

AntibioticMixing TechniqueApproximate Set Time*
Amikacin**  (500mg)Non-Standard – Liquid50 minutes**
Gentamicin  (160-400mg)Standard – Liquid20 minutes
Vancomycin  (500mg-1g)Standard – Powder10 minutes
Cefazolin (500mg-1g)Non-Standard – Powder15 minutes
Tobramycin  (500mg-1g)Non-Standard – Powder35 minutes
Ceftazidime  (500mg-1g)Non-Standard – Powder25 Minutes
Meropenem  (500mg-1g)Non-Standard – Powder25 minutes
Ampicillin/Sulbactam (750mg)Non-Standard – Powder30 minutes
Ceftiofur  (500mg)Non-Standard – Powder30 minutes
Amphotericin B  (50mg)Non-Standard – Powder95 minutes

* Set times vary based on type and dosage of antibiotic. It is therefore advisable to prepare beads allowing for adequate set time.

** 50 minute set time is based on 2ml of liquid amikacin (250mg/ml) and 2ml of Mixing Solution. If 4ml of liquid amikacin (250mg/ml) is mixed (no Mixing Solution required), set time will be approximately 4 hours.

Mixing Instructions

1Empty KERRIER powder into mixing bowl
2Add antibiotic powder to mixing bowl and combine
3Add mixing solution (4ml saline) to mixing bowl
4Use mixing tool to stir until paste is formed
5Use mixing tool to spread paste into either 3mm or 5mm cavities of bead mold mat
6Allow to set, then flex mold mat to release beads
7Compress bead between thumb and finger to ensure fully set

CAUTION: A total of 4ml of liquid is required to mix KERRIER powder to a paste. Combinations of liquid antibiotics and mixing solution (saline) must equal 4ml.

1Empty KERRIER powder into mixing bowl
2Add liquid antibiotic to mixing bowl
3If needed, add additional mixing solution (saline) to equal a total of 4ml of liquid to mixing bowl
4Use mixing tool to stir until paste is formed
5Use mixing tool to spread paste into either 3mm or 5mm cavities of bead mat
6Allow to set, then flex mold mat to release beads
7Compress bead between thumb and finger to ensure fully set

NOTE: For slow setting antibiotics a Non-Standard technique should be used to accelerate set time. Mixing KERRIER powder with mixing solution (saline) first without antibiotic, will jump start the setting process – accelerating set time.

1Empty KERRIER powder into mixing bowl
2Add mixing solution (4ml saline) to mixing bowl
3Use mixing tool to stir for 60 seconds
4Add antibiotic powder to mixing bowl
5Use mixing tool to stir for 30 seconds until paste formed
6Use mixing tool to spread paste into either 3mm or 5mm cavities of bead mat
7Allow to set, then flex mold mat to release beads
8Compress bead between thumb and finger to ensure fully set

NOTE: For slow setting antibiotics (example: Amikacin), a Non-Standard technique should be used to accelerate set time. Mixing KERRIER powder with mixing solution (saline) first without antibiotic, will jump start the setting process – accelerating set time.

CAUTION: A total of 4ml of liquid is required to mix KERRIER powder to a paste. Combinations of liquid antibiotics and mixing solution (saline) must equal 4ml.

1Empty KERRIER powder into mixing bowl
2Determine volume of liquid antibiotic to be used
3If needed, calculate amount of mixing solution (saline) needed to equal the required 4ml of total liquid
4Add calculated amount of mixing solution (saline) to mixing bowl (without antibiotic) and stir thoroughly for 60 seconds
5Add liquid antibiotic to mixing bowl and stir for 30 seconds until a paste is formed
6Use mixing tool to spread paste into either 3mm or 5mm cavities of bead mat
7Allow to set, then flex mold mat to release beads
8Compress bead between thumb and finger to ensure fully set